San Francisco 49ers at Arizona Cardinals: final score & recap
San Francisco 49ers beat Arizona Cardinals 41-22 in Week 11. Arizona Cardinals actually out-gained San Francisco 49ers 488 to 281 total yards despite losing. San Francisco 49ers won the turnover battle.
41-22
Final score
SF at ARI
12-5
SF record
2025 season
3-14
ARI record
2025 season
35.1
Top performer
Christian McCaffrey · 35.1 PPR pts
SUN, NOV 16, 2025
41 – 22
State Farm Stadium
Score by quarter
Team stats
Box scoreTotal yards
Passing yards
Rushing yards
Red zone4-5 (80%) / 3-5 (60%)
3rd down3-9 (33%) / 6-14 (43%)
Time of possession25:45 / 34:15
Turnovers0 / 3
Top performers
13 car · 81 yds · 2 TD · 5/6 rec · 40 yds · 1 TD
35.1
6/6 rec · 67 yds · 2 TD
24.7
Brock Purdy QB
19/26 · 200 yds · 3 TD · 1 car · -7 yds
19.3
15/18 rec · 185 yds
33.5
Trey McBride TE
10/11 rec · 115 yds · 1 TD
27.5
47/57 · 452 yds · 2 TD · 2 car · -2 yds
21.9
Key plays
api-sports /games/eventsFirstTDChristian McCaffrey 1 Yd Rush (Eddy Pineiro Kick)7-0
FirstTDGeorge Kittle 30 Yd pass from Brock Purdy (Eddy Pineiro PAT blocked)13-0
FirstTDBam Knight 6 Yd Rush (Chad Ryland Kick)13-7
SecondTDChristian McCaffrey 9 Yd pass from Brock Purdy (Eddy Pineiro PAT Failed)19-7
SecondFGChad Ryland 26 Yd Field Goal19-10
SecondFGEddy Pineiro 48 Yd Field Goal22-10
SecondFGEddy Pineiro 47 Yd Field Goal25-10
ThirdFGEddy Pineiro 47 Yd Field Goal28-10
ThirdTDGeorge Kittle 4 Yd pass from Brock Purdy (Eddy Pineiro Kick)35-10
FourthTDTrey McBride 10 Yd pass from Jacoby Brissett (Two-Point Run Conversion Failed)35-16
FourthTDChristian McCaffrey 4 Yd Rush (Two-Point Pass Conversion Failed)41-16
FourthTDGreg Dortch 17 Yd pass from Jacoby Brissett (Two-Point Pass Conversion Failed)41-22
Game info
KickoffSun, Nov 16, 2025
VenueState Farm Stadium
Week11
Season series
Week 3San Francisco 49ers won 15-16